1) Cryo Preservation Bags
Cell and cellular components, tissues, and blood and blood components are all preserved in cryo preservation bags. Biological samples can be cryo preserved in freezing bags down to -196°C in both the liquid and vapor phases. Cells (primary cells and cell lines), cellular components, blood and blood components, tissues, and other biological products (vaccines, proteins, exosomes, etc.) are frozen and cryo preserved using freezing bags for use in a variety of therapeutic modalities, including stem cell therapy, CAR-T cell therapy, NK cell therapy, gene therapy, tissue engineering, and regenerative medicine. Ethylene-vinyl acetate (EVA), often known as polyolefin, is a particular grade used to make freezing bags. They are very puncture resistant and maintain their suppleness at subfreezing temperatures. Due to their resistance to gas and liquid permeation, freezing bags make cross-contamination-free storage and culture possible.
Advantages
For optimal freezing and thawing operations of cell, gene, and tissue treatment and bioprocess applications, freezing bags are pre-assembled, single-use, gamma-sterilized, closed systems. They are specifically made for long-term cryo storage and controlled freezing and thawing. There are different sizes of freezer bags with single, dual, and multi-compartment top and bottom tubes. A single filling process can easily distribute samples into a variety of smaller bags (for various QC tests) and bigger storage bags using freezing bags. As a result, minimal human welds and seals are required, lowering the danger of contamination, and increasing usability.
2) EVA Bags
For the collection, processing, and storage of blood and blood components, cells, cellular components, etc., EVA Transfer Bags (Single, Double, and Triple) are employed. High molecular weight EVA of a specific grade is used to make EVA transfer bags.
All machinery and tools used to produce EVA bags go through the proper validation processes. The transfer bags are employed in a variety of applications and are utilized to gather process, and transfer cells, cellular components, and blood as well.
Features
• Numerous product versions are possible thanks to the modular design.
• System of freely adjustable tubes.
• Spike entrance ports are present or absent.
• Spikes with an ergonomic shape for ease of use.
• Grip tab provides quick access to ports.
• port with tamper-evident spikes.
• assurance of traceability.
• labels that are clear and precise.
• Rounded shoulder design.
• maximizes product recovery.
• Every production lot satisfies the Sterility Assurance Level.
• Clean and perfect inside extrusion tubing.
• Each batch contains faultless parts of the highest possible quality.
• Quality was double-checked.
3) PVC Bags
Special medical-grade PVC and DEHP-free PVC are used to make transfer bags. The transfer bags are employed in a variety of applications, including the collection, processing, and transfer of blood and blood components, cells, and cellular components.
Transfer bags come in a variety of configurations and offer versatility for numerous applications. All machinery and tools used to produce PVC bags go through the proper validation processes. PVC Transfer bags have been approved for storage at -80°C.
Features
• Leads with Spikes-Spiked leads offer flexibility for open or closed system processing.
• 7-inch manifold-Product loss is minimized and cryo precipitated AHF recovery is increased with a 7-inch manifold.
• Prevents Product Loss-Standard Y-connected tubing leads related product loss is eliminated by the 6-to-1 manifold tubing connector.
• Control of the process-The process of pooling is managed by a temporary clamp that is positioned between the manifold and the transfer bag.
4) Cell Washing Sets
The purpose of a cell washing set is to remove or reduce the quantities of cryo protectant (DMSO) to wash the nucleated stem cells found in peripheral & cord blood. The recipient patients are toxic when 10% (or more) of the cryo protectant (DMSO) is present in the product, which is crucial for pediatric patients. Therefore, after defrosting the nucleated/stem cell product, DMSO removal is necessary.
Features
• Two 250 ml DEHP-free PVC transfer bags, two multiple-use sample aspiration sites, two spikes, and one female lure for sample transfer make up the product. The thawed unit is cleaned with a Dextran/albumin solution in the first bag. The concentrated stem cell supernatant is transferred to the other bag.
• The possibility of contamination is eliminated by the close system transfer of thawed samples by ABS spikes in the Cell washing set.
• PVC transfer bags with smooth embossing structures do not properly remove the supernatant from the transfer bag and do not catch cells.
• To avoid the injection process and lower the risk of contamination and leakage, a needle-free connection can be offered. Even once the syringe is disconnected, this method guarantees a closed system.
• There are hanger holes available to make carrying the bags simple.
